Try Grass Restaurant & Lounge (28 NE 40th St., 305-573-3355) for Asian-infused cuisine, then groove to tunes ranging from R&B to deep house. Warning: the doormen are famously finicky. If you get velvet-roped, stroll across the street to Piccadilly Garden (35 NE 40th St., 305-573-8221). Feast on stone crabs or hang at the bar, which looks like an old English pub. It’s all about dancing at SoHo Lounge (175 NE 36th St., 305-576-1988) three rooms with DJs and live acts playing everything from ’80s retro music to indie rock. At I/O Lounge (30 NE 14th St., 305-358-8007), check out Latin funk band the Spam Allstars on Thursdays or DJs spinning electro-pop on Saturdays. The kitchen at One Ninety (190 NE 46th St., 305-576-9779) makes tapas till 3 a.m., and the live music ranges from rock to Cuban rumba. And after partying on Saturday, you can go back for a savory Sunday brunch. Hasta pronto.