And with the Colts getting their footing with three straight wins, this could turn into a shootout between Andrew Luck and Tom Brady

PHOTOS: Week 6 action | Packers and Patriots setting up undefeated Super Bowl 50

We’ve got the latest odds, lines and analysis for Week 6 from our experts. Here are some of the key games for this week.

Patriots at Colts against the spread

When Indianapolis has had a healthy Andrew Luck, it has never beaten New England. The Patriots have won those four meetings by the scores of 59-24, 43-22, 42-20 and 45-7. Nothing has to give here, with Tom Brady having superfluous motivation and Luck, if he plays, doing so with a sore shoulder. As usual, the Patriots will deflate the Colts’ hopes with a power running game, courtesy of LeGarrette Blount. Lather, rinse, repeat. Patriots win 38-17 and cover the spread. 

Ivyer’s Week 6 picks against the spread

Chargers at Packers straight-up pick

The Chargers had no business losing Monday night to a team that spent most of the game almost trying to find a way to lose. Weather isn’t likely to be a factor at Lambeau this early, but why trust the Chargers crossing time zones and playing Aaron Rodgers and Co.? They couldn’t handle 78-year-old Mike Vick in their own building. Packers, 34-20.

Steele’s straight up Week 6 picks

Panthers at Seahawks odds and lines

Line: Seattle -7

Total: 41

Linesmakers take:This has the look of a shutout. The Seahawks have been struggling offensively, but we’ve got that defense on our side. Carolina will have trouble moving the ball, which makes UNDER 41 look good, and the Seattle D will set the offense up for easy scores. Predicted score: 23-3.

Full Week 6 betting lines and odds

NFL Week 6 picks lines and odds

NFL Week 6 picks against the spread

NFL Week 6 picks straight up

NFL Week 6 odds and lines